Substrate Specificity and Oligomerization of Human GMP Synthetase
نویسندگان
چکیده
منابع مشابه
Substrate specificity of acetyl coenzyme A synthetase.
Acetyl coenzyme A synthetase (EC 6.2.1.1) has been examined for its ability to accept various carboxylic acids as substrates in place of acetic acid. The activity of the enzyme with these substrates was monitored using a coupled enzyme assay and high pressure liquid chromatography (HPLC) analysis. Short chain carboxylic acids were found to be active including: propionic, acrylic, fluoroacetic, ...
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It is generally accepted that in the first phase of protein biosynthesis, amino acid-specific enzymes, the aminoacyl-ribonucleic acid synthetases, carry out the activation of the various amino acids, and that the exacting specificity of these enzymes extends to the transfer of the amino acid to a particular soluble ribonucleic acid. Several investigators (l-5) have achieved the purification of ...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 2013
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2013.06.032